Multistrain probiotics did not reduce the incidence of MDRO+ colonization at day 30 of life in preterm infants but modulated their microbiome toward eubiosis.
Mirikizumab treatment significantly improved fatigue in patients with moderately to severely active CD, which was sustained to W104. The improvement in fatigue was correlated with improvement in clinical measures and was strongly correlated with improvement in QoL.
Although microbial pathogens were not prevalent, we found several MAGs harboring genes related to antibiotic resistance, highlighting that dairy industry surfaces represent a potential hotspot for antimicrobial resistance (AR) spreading along the food chain.
This interview after the 'ESMO GI Cancers 2024' congress was an opportunity for in-depth study and discussion of new developments in GI oncology.
Gastrointestinal tumours occur most frequently in people over 70. But how does the treatment of geriatric patients differ from that of younger patients?
Long-term daily aspirin intake may help prevent colorectal cancer development and progression but the mechanisms involved are still unclear.
Could bacteria or viruses be rendered harmless by tomatoes or its products? Researchers investigated if tomato substances work against S. typhi.
Precision medicine is revolutionising treatments for colon cancer and other gastrointestinal malignancies by identifying biomarkers for personalised therapies.
Gastrointestinal biofilms are highly heterogenic and spatially organized polymicrobial communities that can expand and cover large areas in the gastrointestinal tract.
Glycolysis in HSCs amplifies liver fibrosis by promoting fibrogenic EV release in the hepatic pericentral zone, which represents a potential therapeutic target.
The practice of routine UGI endoscopy before elective cholecystectomy has been justified by the finding of active UGI pathology which warranted treatment in a significant proportion of patients with presumed symptomatic gallstones in an African setting.
In this diagnostic study validating a prediction model, the model demonstrated excellent accuracy. At a score of at least 6 points, prediction model accuracy and performance were optimized, serious alternative diagnoses were uncommon, and diagnostic yield of early imaging was low.
This systematic review and meta-analysis suggests that there is an increased risk of SIBO in patients with IF and that PN, and potentially, the use of PPI/acid-suppressing agents is risk factors for SIBO development in patients with IF.
The prevalence of MASLD was greater among food-insecure adolescents vs food-secure ones (17.4% vs 9.4%) and adolescents living with a low HH income vs those with a higher HH income (15.0% vs 7.2%) and living with a head of HH with a lower education level vs one with a higher education level (18.0% vs 8.2%) (P < 0.05).
Our data support the murine model to study OCTN1 genetic contribution to inflammatory bowel diseases. This could be the first step towards the recognition of this membrane transporter as a biomarker in inflammatory conditions and a predictor of response to therapies.
The intestinal microbiome is essential in many body processes. Could prebiotic food intake benefit intestinal flora in intestinal polyps or colorectal carcinoma?
Gastro-oesophageal reflux and regurgitation often cause parental concern, but only few babies have a pathology that requires treatment.
There was evidence for a reduction in recurrent bleeding from peptic ulcers with adherent clots treated with endoscopic hemostatic techniques compared with medical management alone but no difference in rates of mortality or need for surgery.
This Review discusses the future requirements for intelligent capsule robots, providing a comparative evaluation of various methods’ merits and disadvantages, and highlighting recent developments in six technologies relevant to WCE.
The findings of this cohort study indicate that a high genetic risk of GC may be counteracted by H pylori treatment, suggesting primary prevention could be tailored to genetic risk for more effective prevention.