This study revealed the critical value of biomarkers related to ferroptosis serving as novel predictive biomarkers for patients with LAGC receiving NAC.
These findings showed that OOACs offer more physiologically relevant environments, promote deeper cellular differentiation and increased cellular tractability when seeded as ASCs rather than classical organoid aggregates.
GI endoscopy, CT and MRI are indispensable in IBD care but carry considerable environmental costs. The broader adoption of IUS offers a clinically effective, low-carbon alternative that can contribute to more sustainable IBD management, aligning with planetary health goals.
A pilot study shows significant differences in the gut microbiome between anxious and non-anxious individuals.
News about the skin-gut-brain axis: Innovative findings on disease mechanisms promise advances in diagnosis and therapy.
These findings suggest protein intake does not benefit cognitive function in older adults. Negative associations may relate to protein food sources.
In patients with HBV-related cirrhosis, the aspirin-treated group showed a significantly lower risk of HCC than the untreated group, whereas the risk of GI bleeding was significantly higher in the aspirin-treated group.
Randomized controlled trials of glutamine in the prevention of chemotherapy-associated diarrhea of colorectal cancer were retrieved from the Cochrane Library, Pubmed, EMBASE, CNKI, and Wanfang by computer up to August 1, 2024.
In this study, we examined whether sociodemographic details were associated with differences in LLM-generated recommendations for gastroenterology presentations.
The global burden of metabolic diseases is increasing, but estimates of their impact on primary liver cancer are uncertain. We aimed to assess the global burden of primary liver cancer attributable to metabolic risk factors, including high body mass index (BMI) and high fasting plasma glucose (FPG) levels, between 1990 and 2021.
In a prospective 12-week intervention trial, we evaluated the effects of six different plant-based fermented pickles (~ 50 g/day) on clinical, inflammatory, and gut microbiota parameters in a cohort of women (n = 230) in a rural setting with a high prevalence of undernutrition.
The phase 3 ESSENCE trial, published in NEJM, reports that once-weekly semaglutide 2.4 mg achieves significant histologic improvements in patients with MASH and stage F2–F3 fibrosis.
Very-early-onset inflammatory bowel disease (VEO-IBD) is a form of IBD that manifests in infants and young children, with a significant proportion of them carrying interleukin 10 receptor alpha (IL-10RA) mutations.
Gastrointestinal tract cancer is increasing at an unprecedented rate among younger adults worldwide, with colorectal cancer in 15- to 19-year-olds rising by 333%, for example.
Despite the pathophysiology caused by acid-GER events, human milk properties may provide better adaptation and modulation of neurosensory and neuromotor responses upon esophageal provocation.
This study highlighted the role of the GCSI in assessing and monitoring gastroparesis, particularly in resource-limited settings. Diabetic GP differs in clinical presentation and management from other types of GP.
A watch-and-wait approach in patients with high probability of spontaneous CBDS passage could avoid unnecessary ERCP and related adverse events in these patients. Further large-scale, prospective studies are needed to validate these findings.
This narrative review summarizes the current knowledge on using intestinal ultrasound (IUS) in patients with Crohn’s disease. The benefits and challenges of using IUS in clinical trials and real-world practice are discussed.
Dysbiosis of the salivary microbiota was observed in subjects with gastroesophageal reflux symptoms (GERSs) alone, as well as in those with combined conditions such as GERS and esophagitis, or esophagitis and Barrett's esophagus.
A total of 85 524 women diagnosed with cervical cancer between 1975 and 2021 were identified, with a follow-up of 822 630 person-years. Among these women, 64 cases of anal cancer were diagnosed.