• Leukaemia Biology Debate: AML Focus

    AML reveals a complex interplay between malignant cells and their environment where disease progression and treatment response is orchestrated.

  • Allo-HSCT in Intermediate-Risk AML: Is It Needed?

    The journey to unravelling the complexities of AML treatment, especially in intermediate-risk patients, evolves as novel diagnositcs and therapies are embraced.

  • AML Classifications: WHO vs ICC 2022 Update

    Besides WHO's classification, ICC's system for AML diagnosis and treatment is also available since 2022. How do they differ and which should be followed?

  • Parkinson's: a diabetes drug could delay the progression of motor symptoms

    A type 2 diabetes drug slowed the progression of Parkinson's disease symptoms, according to a French study testing lixisenatide effects on 156 patients.

  • Virtual reality against cancer pain

    A new study showed that VR provided greater pain relief than control in adult patients with moderate-to-severe pain related to cancer and its therapies.

  • Scabies: Permethrin is not really effective anymore

    The standard treatment for scabies is permethrin, but it is becoming less due to mutations in the scabies mite that have led to resistance development.

  • Patients with IBD and high abdominal fat may need more infliximab

    Some Crohn's disease or ulcerative colitis patients do not respond to infliximab or its effect diminish for them. This could be related to visceral fat mass.

  • New ASCO and SSO guidelines create global consensus

    BRCA1 and BRCA2 mutations are crucial in hereditary breast and ovarian cancer treatment and prevention. Finding suitable germline-analysis patients is hard.

  • Analysis: Electronic cigarettes and cancer risk

    A study hints that e-cigarettes cause the same epigenetic changes found in cancer patients and traditional cigarette smokers. But the study has many limitations.

  • Cervical carcinoma: When is surgery an option?

    Cervical cancer is one of the most common forms of cancer in women. Various surgical and conservative treatments exist, but which therapy is suitable for which patient?

  • Metastasised breast cancer: Are there new treatment options?

    In breast cancer, metastases may occur in body areas not always easy to treat. But there are two new treatment options for these patients.

  • Does the pill increase the risk of anxiety disorders?

    Oral contraceptives have a significant impact on hormonal balance. But they may also alter emotional regulation and enhance anxiety disorders.

  • Recurrent endometrial cancer: Which therapy for whom?

    Recurrent endometrial carcinoma is associated with a 5-year survival rate of 20-25%. How can longer and progression-free survival be achieved?

  • Hyper... hypervaccinated! Is there a vaccination limit for COVID-19?

    A German man made headlines after receiving 217 COVID-19 vaccinations. Could it give super immunity? Or are these cases damaging the immune system?

  • Mental stress leaves its mark on the brain

    Corona, war, climate worries, are all potential triggers for mental stress. This may lead to irritability, a deteriorating memory or sleep disorders.

  • Interview: Assisted suicide, more humanity and less bureaucracy for the dying

    Dr Bernd Maier (Head Physician, St. Josef's Hospital, Wiesbaden, Germany) discusses today's stances in medicine and society on the wish to die and assisted suicide.

  • Depression: Sports are as effective as SSRIs

    Data from a recent network meta-analysis suggest that physical activity should be given a much more central place in the treatment of depression.

  • NERD: no increased risk of oesophageal cancer

    Do patients with non-erosive gastro-oesophageal reflux need regular follow-up endoscopies to prevent cancer? A long-term cohort study argues against this.

  • Otoferlin-related deafness: gene therapy opens a path to a cure

    Can gene therapies lead to a life without deafness? Revolutionary approaches and advances in the treatment of Otoferlin deafness.

  • Rheumatoid arthritis: fitness is more important than inflammation management

    It is well-known that RA patients have a higher mortality risk, but many physicians and patients may be less aware of the benefits of physical fitness in RA.

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