Researchers show that water loss in the cell, the so-called osmotic stress, sets in motion cellular waste disposal, which occurs through an interaction of autophagy and lysosomes; with implications for neurodegenerative diseases.
The EUPROMS study represents the first patient-driven quality-of-life (QoL) data collection and revealed specific long-term complaints correlating with a given treatment.
Researchers found that medication and psychotherapy do not differ in the acute treatment of individual symptoms. The researchers' goal remains to develop a more individually adapted therapy.
Recent studies suggest that steroid sulfatase (STS) can drive prostate cancer and initiate resistance through an alternative androgen synthesis.
Some people are better protected against UTIs because their bodies produce higher levels of uromodulin. A research team discovered how the helper protein works, with possible implications for UTI treatment and prevention.
A 10-years single-center study reported that substantially more men complain of reduced sexual desire than a decade ago. Conversely, fewer men complain of erectile dysfunction and premature ejaculation.
New findings show that urosepsis is associated with lower mortality than sepsis derived from other sites, but if appropriate measures are not taken, 10-15% will develop a recurrent urosepsis.
The EAU20 virtual meeting featured a thematic session looking at the controversy in renal cancer surgery considering the timing and necessity of cytoreductive nephrectomy.
The trend in continental birth rate falls is partly related to economic uncertainty, as demographers from the Austrian Academy of Sciences show using data from the European Demographic Data Sheet.
Prof. Axel Merseburger reviewed the recent evidence testing immuno-oncology (IO) in combination with tyrosine kinase inhibitors (TKIs) in metastatic renal cell carcinoma (mRCC).
Pharmacologists have succeeded in detecting minute amounts of the coronavirus SARS-CoV-2 using mass spectrometry in solutions with which COVID-19 patients gargled. The new method could serve as a supplement to previously used tests.
Adding docetaxel to antiandrogen treatment improves progression-free survival (PFS) in prostate cancer patients with prostate-specific antigen (PSA) relapse.
Aquablation demonstrated a significantly lower rate of sexual dysfunction at the primary safety endpoint of 3 months compared with transurethral resection of the prostate (TURP), according to phase-3 data.
In his state-of-the-art lecture, Prof. Leendert Looijenga discussed the connection between infertility and testicular cancer1. Both molecular associations and putative causality were reviewed.
New findings from the large, multicentre IRON study demonstrate that robot-assisted partial nephrectomy (RAPN) is associated with lower morbidity and similar oncologic and long-term renal function outcomes compared with open partial nephrectomy (OPN).
Labeled prostate-specific membrane antigen in PET-CT fusion was superior in specificity and sensitivity to conventional imaging in pre-treatment staging of intermediate and high-risk localized prostate cancer.
The neurological history from male LUTS patients or their partners is essential. Urologists should perform a careful physical exam and perhaps a referral to neurologists prior to any invasive or irreversible treatment.
A highly contagious disease breaks out in Italy and threatens to contaminate the whole of Europe. Sick people remain in isolation. Caregivers risk their lives to protect them in a world in crisis. This disease had nothing to do with the medical field.
The trial demonstrated a significant survival advantage for intermediate and poor-risk patients with metastatic renal-cell carcinoma who received pembrolizumab + axitinib as compared to those receiving sunitinib.
Prof. Yohann Loriot discussed novel treatment options beyond immunotherapy, urging a better understanding of tumor biology towards identifying new targets and facilitating precision medicine.