Increased serum concentrations of neurofilament light chains (NFL), also known as neurofilament light polypeptides, are associated with poorer neurological functions, according to a large real-world study.
According to a recent study, the 5-alpha-reductase inhibitors reduce serum prostate-specific antigen (PSA) levels by half, which can lead to an underestimation of a possible risk of prostate cancer.
A recent meta-analysis from the USA and Germany investigated the question of whether surgical removal of hematomas improves any functional outcome.
Women with diabetes have a significantly higher risk of stillbirth during pregnancy. A data evaluation from two Scottish registries has shown that factors such as poorly controlled high long-term blood sugar, overweight, or obesity are behind this risk.
Two studies recently published in Lancet Neurology indicate that an acute lowering of systolic blood pressure below 140mm Hg is feasible and safe. However, the minimization of blood pressure fluctuations seems to be of prognostic importance.
The conclusions were reached by Jordan Axelrad and colleagues in a retrospective multi-center study for the New York Crohn's and Colitis Organization (NYCOO).
Ankylosing spondylitis (AS) patients are often left alone in coping with fatigue, the third most common AS symptom after stiffness and pain.
Results of the 'Harvard Aging Brain Study' suggest that higher physical activity has a protective effect against β amyloid-associated cognitive decline and neurodegeneration.
A new study shows that stress-perfusion MRI scans are similarly effective to FFR measurements for stable angina pectoris, and more so, the scans avoid unnecessary cardiac catheter examinations.
Heart failure risk in diabetes is significantly higher. For women with type 1 diabetes, heart failure risk is 47% higher than that of men with this condition. A recent analysis of 14 cohort studies has shown that such a difference is not as pronounced for type 2 diabetes.
The optimal follow-up and monitoring of patients with resected non-metastatic colon carcinoma were unclear until now. However, circulating tumor DNA (ctDNA) in the blood could solve this problem in practice, as a recent study has shown.
The company, which is responsible for the largest drug price increase in US history, has bribed doctors and employees to increase sales, according to documents recently unsealed in federal court.
Xenon therapy shortly after TBI reduces neuronal cell loss and chronic neuroinflammation and improves survival and clinically relevant outcomes, such as long-term cognitive function.
Very little is known about the prescribing practices of clinically active oncologists with regard to biosimilars. What do physicians need to know to be able to safely use these new drugs in the future?
"Patient-Reported Outcomes" play an increasingly important role in the assessment of drugs. In this respect, monotherapy with Sarilumab is superior to monotherapy with Adalimumab in patients with rheumatoid arthritis (RA) according to data from the MONARCH study.
Patients with type 2 diabetes have a significantly higher risk of developing cancer. However, the risk in women and men is influenced very differently and not all cancer entities are affected equally, as a large population study from China has shown.
People who sit for a very long time every day run the risk of dying earlier. Physical activity is recommended as compensation. It was unclear how much sport is needed to pay off the "sitting debt" but a new study now provides more certainty.
After decades of uncertainty European scientists compiled 183 risk assessments from 53 meta-studies for 71 environmental factors influencing chronic inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC).
Surprising findings from the 'RESTART' study suggest that resuming pre-existing platelet inhibitor therapy (compared to avoiding it) may reduce the risk of recurrent symptomatic intracerebral hemorrhages.
In an Italian cohort study, the attempt to stop glucocorticoids in patients with systemic lupus erythematosus (SLE) was successful in the majority of cases.