• Type 2 diabetes nutrition: Calorie restriction is not the only issue

    Changing eating habits is crucial in the prevention and treatment of type 2 diabetes. How can patients impact blood sugar levels and lipid parameters, and prevent acute and chronic diabetes complications?

  • Some metastatic breast cancer patients have a high proportion of risk mutations

    A recent case study showed that up to 14% of patients with metastatic breast cancer possessed a higher number of hereditary risk genes in multi-tests. Several pathogenic and probably pathogenic germline variants were found, including BRCA1 and BRCA2 mutations.

  • A "time span within normal range" can also correlate with diabetes complications

    The HbA1C value is considered the gold standard for blood glucose monitoring, but it has limitations. US scientists have conducted a study to determine an alternative to predict microvascular complications.

  • Breaking through outdated structures in disease risk and prognosis with multimodal approaches

    Colorectal cancer (CRC) is a disease whose course and its outcomes are also determined by socioeconomic (SE) and ethnic factors. A recent study investigates how these inequalities could be most effectively addressed.

  • Real-world data backs potential of serum neurofilament light chain (sNFL) as biomarkers for multiple sclerosis

    Increased serum concentrations of neurofilament light chains (NFL), also known as neurofilament light polypeptides, are associated with poorer neurological functions, according to a large real-world study.

  • BPH therapy with 5-ARI halves the PSA value

    According to a recent study, the 5-alpha-reductase inhibitors reduce serum prostate-specific antigen (PSA) levels by half, which can lead to an underestimation of a possible risk of prostate cancer.

  • Spontaneous cerebellar hemorrhages: Go surgical or stay conservative?

    A recent meta-analysis from the USA and Germany investigated the question of whether surgical removal of hematomas improves any functional outcome.

  • Women with diabetes present a higher risk of stillbirth

    Women with diabetes have a significantly higher risk of stillbirth during pregnancy. A data evaluation from two Scottish registries has shown that factors such as poorly controlled high long-term blood sugar, overweight, or obesity are behind this risk.

  • Blood pressure reduction in ICH: what is important?

    Two studies recently published in Lancet Neurology indicate that an acute lowering of systolic blood pressure below 140mm Hg is feasible and safe. However, the minimization of blood pressure fluctuations seems to be of prognostic importance.

  • IBD and hormone therapies for cancer

    The conclusions were reached by Jordan Axelrad and colleagues in a retrospective multi-center study for the New York Crohn's and Colitis Organization (NYCOO).

  • Ankylosing spondylitis: Severe fatigue impairs everyday life

    Ankylosing spondylitis (AS) patients are often left alone in coping with fatigue, the third most common AS symptom after stiffness and pain.

  • Does exercise influence the link between Aβ load and cognitive decline/neurodegeneration?

    Results of the 'Harvard Aging Brain Study' suggest that higher physical activity has a protective effect against β amyloid-associated cognitive decline and neurodegeneration.

  • MRI use instead of cardiac catheter for stable angina pectoris?

    A new study shows that stress-perfusion MRI scans are similarly effective to FFR measurements for stable angina pectoris, and more so, the scans avoid unnecessary cardiac catheter examinations.

  • Increased risk of heart failure in diabetes

    Heart failure risk in diabetes is significantly higher. For women with type 1 diabetes, heart failure risk is 47% higher than that of men with this condition. A recent analysis of 14 cohort studies has shown that such a difference is not as pronounced for type 2 diabetes.

  • Circulating tumor DNA (ctDNA) in follow-up care

    The optimal follow-up and monitoring of patients with resected non-metastatic colon carcinoma were unclear until now. However, circulating tumor DNA (ctDNA) in the blood could solve this problem in practice, as a recent study has shown.

  • USA: Pharmaceutical company bribed doctors into prescribing overpriced drug

    The company, which is responsible for the largest drug price increase in US history, has bribed doctors and employees to increase sales, according to documents recently unsealed in federal court.

  • Xenon can stop secondary damage after Traumatic Brain Injury (TBI)

    Xenon therapy shortly after TBI reduces neuronal cell loss and chronic neuroinflammation and improves survival and clinically relevant outcomes, such as long-term cognitive function.

  • Oncologists want more information about biosimilars

    Very little is known about the prescribing practices of clinically active oncologists with regard to biosimilars. What do physicians need to know to be able to safely use these new drugs in the future?

  • "Patient-reported outcomes” in rheumatoid arthritis

    "Patient-Reported Outcomes" play an increasingly important role in the assessment of drugs. In this respect, monotherapy with Sarilumab is superior to monotherapy with Adalimumab in patients with rheumatoid arthritis (RA) according to data from the MONARCH study.

  • Increased risk of cancer in type 2 diabetes patients

    Patients with type 2 diabetes have a significantly higher risk of developing cancer. However, the risk in women and men is influenced very differently and not all cancer entities are affected equally, as a large population study from China has shown.

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