• Topical pan-JAK inhibitor mitigates inflammatory biomarkers in frontal fibrosing alopecia

    Delgocitinib was associated with a reduction in interferon gamma (IFN-γ), chemokine ligand (CXCL)9, and CXCL10 in the treatment of FFA.

  • PsoBest registry: Biologics have become the first choice in moderate-to-severe psoriasis

    A comprehensive analysis from the German Psoriasis Registry (PsoBest) highlights the evolution of systemic drug use for psoriasis over the past 15 years.

  • Atopic dermatitis early in life imposes a lifelong psychosocial burden

    A study including data from over 30,000 participants revealed that early onset of atopic dermatitis (AD) leads to a psychosocial burden throughout adult life.

  • Prurigo nodularis: long-term treatment reduces relapse events

    Withdrawing nemolizumab led to an 8-fold increase in the likelihood of a prurigo nodularis (PN) relapse compared with uninterrupted therapy.

  • Imsidolimab potential future therapeutic avenue for generalised pustular psoriasis

    A single dose of 750 mg imsidolimab yielded a GPPPGA score of clear or almost clear in over half of the participants with GPP after 4 weeks.

  • Autism: diagnosis through the eyes?

    A combination of eye-tracking tests could help to speed up the diagnostic process and make it more efficient, according to the authors.

  • Targeting IL-17A: a promising treatment perspective in hidradenitis suppurativa

    Izokibep treatment for hidradenitis suppurativa (HS) met its primary endpoint of HS Clinical Response (HiSCR)75 in an ongoing phase 3 trial.

  • Bipolar disorder: is magnetic seizure therapy a treatment option?

    In the randomised study, participants were treated either with magnetic seizure therapy (MST) or with Electroconvulsive Therapy (ECT). What were the results?

  • New targets identified for chronic wound healing

    A study using full-thickness human skin punches identified critical molecular targets that could transform the treatment of both acute and chronic wounds.

  • Advanced BCC: histological subtype and time to complete response may predict tumour recurrence

    Histologic risk status at diagnosis and the time needed to achieve complete remission (CR) may influence the prospect of a relapse after HHI treatment.

  • Semaglutide: also beneficial for patients with HS?

    In patients with hidradenitis suppurativa and obesity, therapy led to significant weight loss, reduced flares and improved quality-of-life.

  • Anti-KIT antibody: the next frontier in CSU treatment?

    A novel anti-KIT antibody demonstrated high rates of well-controlled and fully controlled disease after 1 year of treating chronic spontaneous urticaria.

  • IL-13 inhibitor shows safety and efficacy in AD over 3 years

    The EASI90 response in the extension study ADjoin even increased over time with around 80% of patients achieving this high clearance rate at 152 weeks.

  • Atopic hand eczema: similar treatment success for dupilumab and delgocitinib

    Indirect matching-adjusted comparison assessing delgocitinib cream and subcutaneous dupilumab did not detect significant differences in treatment.

  • Soft drinks increase liver cancer and liver-related mortality

    Sugary drinks cause weight gain and heart damage. Regarding liver damage, US researchers argue it may depend on the sweeteners.

  • New research confirms link between perceived stress and psoriasis flare-ups

    The study shows how stress triggers relapses. It was presented at the EADV Congress 2024 and scientifically confirms the correlation for the first time in vivo.

  • Analysis: Sex differences in asthma

    Sex affects how asthma manifests clinically. This is crucial for routine clinical practice and new studies, like those on asthma pharmacological treatments.

  • Salt increases stomach cancer risk by 40%

    In the Asia region, a correlation between high salt consumption and stomach cancer has been established. This is now confirmed in European cancer statistics.

  • Performance of 2021 criteria for the diagnosis of PNSs

    A new study measures the performance of the 2021 criteria for paraneoplastic neurological syndromes in childhood, a rare condition, often difficult to diagnose.

  • Lactobacilli versus antifungals for vaginal candidiasis

    Lactic acid bacteria help to defend against infections and, best of all, there is no risk of resistance developing. but can they keep up with antifungals?

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