• Medical Case: Persistent bleeding after dental extraction

    Persistent bleeding after dental extraction is uncommon and usually resolves with local measures. In some cases, however, bleeding may persist.

  • Sucralose: Does the sweetener interfere with cancer immunotherapy?

    New data shows that the widely used sweetener sucralose can impair the response to PD-1-based immunotherapies in tumor patients, due to triggered changes in the gut microbiome.

  • Breathing exercises as a new treatment for reflux?

    A systematic review examines the question of whether targeted respiratory muscle training can influence the anti-reflux barrier and alleviate reflux symptoms.

  • Medical Case: Refractory ARDS

    A young patient with severe pneumonia deteriorates rapidly despite textbook therapy. ARDS progresses, lab signals diverge from expectations, and clinicians must abandon initial diagnoses.

  • 112: the first therapeutic act in European emergency care

    In the European Union, the emergency number 112 handles the majority of emergency calls and is recognised by almost all citizens.

  • Burnout and suicide risk in physicians

    Burnout and suicide among physicians are not individual failures but predictable outcomes of systemic strain across medical training and practice.

  • CRISPR “n=1”: a new model for personalised therapy

    A single-patient CRISPR therapy challenges how we define drugs, clinical trials, and regulation. Beyond clinical success, it signals a structural shift in medicine.

  • How screens are reshaping sleep health

    Digital habits are disrupting sleep across Europe, especially among adolescents. Why this matters for stress, cognition, and long-term health.

  • ERC Guidelines 2025: a new system-level view on Cardiac Arrest

    The 2025 ERC Guidelines introduce significant evidence-based updates in cardiac arrest epidemiology and management. Dr Enrico Baldi outlines the most relevant changes for clinical practice.

  • Blue Monday: myth, media narrative, and clinical relevance

    Every January, Blue Monday is described as “the most depressing day of the year.” But while the concept lacks scientific basis, winter-related changes in mood are real.

  • Medical Case: An unpleasant honeymoon

    A 32-year-old man develops unexpected erectile difficulties during his honeymoon. Investigations are normal. What is the real diagnosis?

  • Acute hepatitis in children: a post-acute consequence of COVID-19?

    In a European case series involving 12 children with acute hepatitis of unknown cause, pronounced CD8 T-cell infiltrates were found in the liver, along with SARS-CoV-2 proteins.

  • Male sexual dysfunction: beyond biology

    Recent evidence shows how erectile dysfunction, ejaculation disorders and low sexual desire profoundly affect men’s psychological wellbeing, shaping identity, self-esteem and quality of life.

  • Probiotics may improve symptoms in children with autism

    What may seem questionable at first glance has a perfectly plausible explanation: the gut-brain axis as an important mediator between the enteric and central nervous systems.

  • Polygenic Risk Scores in Prostate Cancer

    New data from 2024–2025 show how polygenic risk scores may refine prostate cancer screening and risk stratification, improving early detection while raising important clinical and ethical challenges.

  • Yearly review: Erectile Dysfunction in 2025

    EAU SRH 2025 updates strengthen ED management with structured diagnosis, better PDE5 strategies and clarified testosterone use, highlighting ED as a key indicator of men’s health.

  • Christmas burnout among healthcare professionals

    The holiday season brings heavier workloads, reduced staffing and emotional strain. For many clinicians, Christmas is not a break but an amplifier of burnout risk.

  • Medical Case: A 35-year-old woman with fever and upper abdominal pain after visiting Bangladesh

    After two years in Bangladesh, a 35-year-old woman returns with fever, upper abdominal pain and weakness. Can you diagnose her condition?

  • FRESCO-2 results: Subgroup analyses reveal prolonged survival in mCRC study

    Who benefits most from fruquintinib in metastatic colorectal cancer? A subgroup analysis of the FRESCO-2 study focuses on individuals with long overall survival.

  • Medical Case: A persistent pain, and a delayed question

    A 54-year-old woman has back pain and a long-neglected breast lump. Her clinical journey will require more than a single decision, challenging the tumor board to choose the right steps at the right time.

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