• Somatic mutations accompany humans from beginning to end

    The ageing process leads to function loss and more disease susceptibility. Somatic mutations play a major role in neurodegenerative diseases and cancer.

  • A case of "I don't know!": Tips for patient communication

    Not all disease symptoms are clear and unambiguous. There are often differential diagnoses. What is the best way to communicate diagnostic uncertainty?

  • Sarcoidosis: Mindfulness-based cognitive therapy helpful for fatigue

    A 12-week mindfulness-based online cognitive therapy improved sarcoidosis-associated fatigue, health status, anxiety, and depression symptoms.

  • Coffee: Some may be predisposed to negative kidney effects

    A longitudinal study suggests that high coffee consumption is associated with a nearly tripled risk of kidney dysfunction for adult slow caffeine metabolisers.

  • Global infertility could be human-induced

    Infertility affects about one in six people. According to the WHO, access to fertility treatment should expand, and the topic garner more focus in health research and policy.

  • Chronic kidney disease and diabetes: What's new?

    The therapy of chronic kidney disease and diabetes is very complex and the guidelines are usually flexible. We present the most recent recommendations.

  • Rehab: Activating orthosis for a strong back after vertebral fracture

    Active upright spinal orthoses can improve back pain and kyphosis levels in acute vertebral fractures. It was unclear whether they were also effective in older fractures.

  • Treatment for relatives and friends: yes or no?

    Advice for the aunt, a prescription for the mother, a check-up for the best friend. Physicians occasionally treat their friends and relatives. Is it a good idea?

  • Is the long-term use of PPIs problematic?

    A long-term study of 20,000 people with type 2 diabetes reported that long-term use of PPIs is associated with increased cardiovascular and mortality risks.

  • Appearances do not deceive: those who look younger are also healthier

    Those who look younger than their actual age may be doubly blessed. A study links someone's external appearance and their state of health.

  • Is there an optimal therapy management for uncontrolled glaucoma?

    Glaucoma surgeons focus on filtering surgery and MIGS. We now also have the surgical manipulation of the uveoscleral outflow pathway at our disposal.

  • Prof. Dr. Julia Szendrödi on type 2 diabetes comorbidities and guideline-based therapy

    How can fatty liver, heart, and kidney failure be prevented as type-2 diabetes comorbidities? This interview by Dr. Petra Sandow tackles the issue.

  • Opinion: Women and climate change

    In the climate change era, women are more vulnerable but also powerful promoters of adaptation and mitigation.

  • Malnutrition in cancer patients increases risk of surgery

    Tumour patients often suffer from malnutrition, as gastric cancers drain nutritional supplies. Research on this was limited until a new large-scale global study.

  • Green Medicine: finding the carbon footprint in the operating room

    A new carbon footprint analysis of products used in UK operating rooms shows that 68% of the impact is caused by single-use items, such as gowns, patient drapes and instrument table cloths.

  • Smoking during pregnancy increases risk of premature birth and SIDS

    Smoking during pregnancy has been deemed unsafe for mother and child. New data on child death in pregnant smokers show that there is no safe intake.

  • The Sustainable Doctor's Office: Is it possible?

    Physicians are more committed to climate protection and sustainability. But how can measures also occur in daily practice? We present a view from Germany on the issue.

  • TAPE: Transarterial Periarticular Embolisation for Chronic Pain

    Chronic joint pain occurs frequently in older age. With the method of joint artery embolisation, there is now a minimally invasive treatment alternative to conservative therapy.

  • DMARDs: what to do if surgery is planned?

    Which drugs should be discontinued (or not) before a surgery? SPAQI published relevant new clinical guidelines for rheumatological diseases treatment.

  • GLP-1 agonists and weight loss: up-to-date real-world data

    Patients and practitioners often expect significant weight loss from type 2 diabetes therapy with GLP agonists. But is this realistic? A recent analysis looks into it.

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