Oculocerebral hypopigmentation syndrome

The Type Cross oculocerebral hypopigmentation syndrome is a rare congenital syndrome characterized by poor skin and eye pigmentation, various ocular abnormalities, dwarfism and mental retardation, and progressive neurological outcomes.

The clinical picture varies between patients and may include other abnormalities such as urinary tract malformations or inguinal hernias. The oculo-cerebral hypopigmentation syndrome type Preus is a rare congenital syndrome with poor pigmentation of eyes and hair, short stature, and intellectual deficit.

Other clinical abnormalities, such as sensory hypersensitivity or cataracts, may occur.