Nievergelt syndrome

Nievergelt syndrome is a dominant hereditary rare bone disease that leads to mesomelic dysplasia. It is composed of four feature strains, all from the area of mutiple malformations. The most characteristic features are dysplasias of the elbow joints, synostoses and dysplasia of the lower leg bones, and atypical clumps with extensive synostosis of root bone. The Nievergelt syndrome is a dominant hereditary rare bone disease that belongs to the mesomelic dysplasia. It consists of four feature carriers, all of which originate from the area of mutiple malformations.

Feature carriers are dysplasia of the elbow joints, or synostoses and dysplasia of the lower leg bones and atypical club feet with extensive synostosis of tarsal bones.